References

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  2. Mahe V, Balogh A. Long-term pharmacological treatment of general- ized anxiety disorder. Int Clin Psychopharmacol. 2000;15:99-105.


  3. Tunnicliff G, Raess BU. GABA neurotransmitter activity in human epileptogenic brain. In: Tunnicliff G, Raess BU, eds. GABA mechanisms in epilepsy. New York: Wiley-Liss, 1991:105-120.


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  7. Ketter TA, Post RM, Theodore WH. Positive and negative psychiatric effects of antiepileptic drugs in patients with seizure disorders. Neurology. 1999;53(Suppl 2):S53-S67.


  8. Petty F. GABA and mood disorders: a brief review and hypothesis. J Affect Disord. 1995;34:275-281.


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  11. Commissaris RL, Hill TJ, McMiller LV Jr, et al. Initial subsensitivity to anxiolytic treatments on conflict behavior in rats: parametric studies across drug classes. Pharmacol Biochem Behav. 1995;51:391-396.


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  17. Data on file, Abbott Laboratories (in press).


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  24. Letterman L, Markowitz JS. Gabapentin: a review of published experience in the treatment of bipolar disorder and other psychiatric conditions. Pharmacotherapy. 1999;19(5):565-572.


  25. Ryback R, Ryback L. Gabapentin for behavioral dyscontrol. Am J Psychiatry. 1995;152:1399.


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  27. Neurontin ® package insert, Parke-Davis.


  28. Sybirska E, Seibel JP, Bremner JD, et al. [123]iomazenil SPECT imaging demonstrates significant benzodiazepine receptor reserve in human and nonhuman primate brain. Neuropharmacology. 1993;32:671-680.


  29. Schmidt D, Gram L, Brodie M, et al. Tiagabine in the treatment of epilepsy –– a clinical review with a guide for the prescribing physician. Epilepsy Res. 2000;41:245-251.


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  32. Sheardown MJ, Weis JU, Knutsen LJ. Analgesic effect of the GABA uptake inhibitor NO-328 (N-(4,4-D1(3-methyl-2-thienyl) but-3-1-yl) nipecotic acid). Soc Neurosci Abstr. 1989;15:602.


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  34. Neilson EB. Anxiolytic effect of NO-328, a GABA-uptake inhibitor. Psychopharmacology. 1988;96:S42.


  35. Holden KR, Titus MO. The effect of tiagabine on spasticity in children with intractable epilepsy: a pilot study. Pediatr Neurol. 1999;21:728-730.


  36. Johansen FF, Diemer NH. Enhancement of GABA neuro- transmission after cerebral ischemia in the rat reduces loss of hippocampal CA1 pyramidal cells. Acta Neurol Scand. 1991;84:1-5.


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  38. Schaffer LC, Schaffer CB. Tiagabine and the treatment of refractory bipolar disorder (letter). Am J Psychiatry. 1999; 156:2014-2015.


  39. Grunze H, Erfurth A, Marcuse A, et al. Tiagabine appears not to be efficacious in the treatment of acute mania. J Clin Psychiatry. 1999;60:759-762.


  40. Depakote ® package insert, Abbott Laboratories.
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